The immune suppressive microenvironment of human gliomas depends on the accumulation of bone marrow-derived macrophages in the center of the lesion

BACKGROUND: Systemic and local immune suppression plays a significant role in glioma progression. Glioma microenvironment contains both brain-resident microglial cells (MG) and bone marrow-derived macrophages (BMDM), but the study of their functional and immune regulatory activity has been hampered...

Descripción completa

Detalles Bibliográficos
Autores principales: Pinton, Laura, Masetto, Elena, Vettore, Marina, Solito, Samantha, Magri, Sara, D’Andolfi, Marta, Del Bianco, Paola, Lollo, Giovanna, Benoit, Jean-Pierre, Okada, Hideho, Diaz, Aaron, Della Puppa, Alessandro, Mandruzzato, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391795/
https://www.ncbi.nlm.nih.gov/pubmed/30813960
http://dx.doi.org/10.1186/s40425-019-0536-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391795/
https://www.ncbi.nlm.nih.gov/pubmed/30813960
http://dx.doi.org/10.1186/s40425-019-0536-x

Ejemplares similares