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The immune suppressive microenvironment of human gliomas depends on the accumulation of bone marrow-derived macrophages in the center of the lesion
BACKGROUND: Systemic and local immune suppression plays a significant role in glioma progression. Glioma microenvironment contains both brain-resident microglial cells (MG) and bone marrow-derived macrophages (BMDM), but the study of their functional and immune regulatory activity has been hampered...
Autores principales: | Pinton, Laura, Masetto, Elena, Vettore, Marina, Solito, Samantha, Magri, Sara, D’Andolfi, Marta, Del Bianco, Paola, Lollo, Giovanna, Benoit, Jean-Pierre, Okada, Hideho, Diaz, Aaron, Della Puppa, Alessandro, Mandruzzato, Susanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391795/ https://www.ncbi.nlm.nih.gov/pubmed/30813960 http://dx.doi.org/10.1186/s40425-019-0536-x |
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