A critical role of epigenetic inactivation of miR-9 in EVI1(high) pediatric AML

Ectopic Viral Integration site 1 (EVI1) upregulation is implicated in 10–25% of pediatric acute myeloid leukemia (AML) and has an inferior outcome with current chemotherapy regimens. Here we report that EVI1 upregulation is associated with methylation of the miR-9 promoter and correlated with downre...

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Detalles Bibliográficos
Autores principales: Mittal, Nupur, Li, Liping, Sheng, Yue, Hu, Chao, Li, Fuxing, Zhu, Tongyu, Qiao, Xiaohong, Qian, Zhijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391809/
https://www.ncbi.nlm.nih.gov/pubmed/30813931
http://dx.doi.org/10.1186/s12943-019-0952-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391809/
https://www.ncbi.nlm.nih.gov/pubmed/30813931
http://dx.doi.org/10.1186/s12943-019-0952-z

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