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Significant improvement of miRNA target prediction accuracy in large datasets using meta-strategy based on comprehensive voting and artificial neural networks

BACKGROUND: Identifying mRNA targets of miRNAs is critical for studying gene expression regulation at the whole-genome level. Multiple computational tools have been developed to predict miRNA:mRNA interactions. Nonetheless, many of these tools are developed in various small datasets, which each repr...

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Detalles Bibliográficos
Autores principales: Zhao, Bi, Xue, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391818/
https://www.ncbi.nlm.nih.gov/pubmed/30813885
http://dx.doi.org/10.1186/s12864-019-5528-1