Functional Genetic Single-Nucleotide Polymorphisms (SNPs) in Cyclin-Dependent Kinase Inhibitor 2A/B (CDKN2A/B) Locus Are Associated with Risk and Prognosis of Osteosarcoma in Chinese Populations

BACKGROUND: Cyclin-dependent kinase inhibitor 2A/B (CDKN2A/B) encodes several tumor suppressor proteins. Aberrant genetic alterations in CDKN2A/B were found in some malignancies, which were believed to be associated with tumor originating and progression. We hypothesized that CDKN2A/B genetic polymo...

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Detalles Bibliográficos
Autores principales: Zhang, Hua-Hui, Mao, Jian-S., Hu, Wei-F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391859/
https://www.ncbi.nlm.nih.gov/pubmed/30774116
http://dx.doi.org/10.12659/MSM.915001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391859/
https://www.ncbi.nlm.nih.gov/pubmed/30774116
http://dx.doi.org/10.12659/MSM.915001

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