Structural basis of coreceptor recognition by HIV-1 envelope spike

HIV-1 envelope glycoprotein [Env; trimeric (gp160)(3) cleaved to (gp120/gp41)(3)] interacts with primary receptor CD4 and coreceptor (e.g. chemokine receptor CCR5 or CXCR4) to promote viral entry by fusing viral and target cell membranes. Encounter of gp120 with the coreceptor was thought to be the...

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Detalles Bibliográficos
Autores principales: Shaik, Md Munan, Peng, Hanqin, Lu, Jianming, Rits-Volloch, Sophia, Xu, Chen, Liao, Maofu, Chen, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391877/
https://www.ncbi.nlm.nih.gov/pubmed/30542158
http://dx.doi.org/10.1038/s41586-018-0804-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391877/
https://www.ncbi.nlm.nih.gov/pubmed/30542158
http://dx.doi.org/10.1038/s41586-018-0804-9

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