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Reciprocal Regulation of KCC2 Trafficking and Synaptic Activity

The main inhibitory neurotransmitter receptors in the adult central nervous system (CNS) are type A γ-aminobutyric acid receptors (GABA(A)Rs) and glycine receptors (GlyRs). Synaptic responses mediated by GlyR and GABA(A)R display a hyperpolarizing shift during development. This shift relies mainly o...

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Detalles Bibliográficos
Autores principales: Côme, Etienne, Heubl, Martin, Schwartz, Eric J., Poncer, Jean Christophe, Lévi, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391895/
https://www.ncbi.nlm.nih.gov/pubmed/30842727
http://dx.doi.org/10.3389/fncel.2019.00048