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Hepcidin as a key iron regulator mediates glucotoxicity-induced pancreatic β-cell dysfunction
It has been well established that glucotoxicity induces pancreatic β-cells dysfunction; however, the precise mechanism remains unclear. Our previous studies demonstrated that high glucose concentrations are associated with decreased hepcidin expression, which inhibits insulin synthesis. In this stud...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Bioscientifica Ltd
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391907/ https://www.ncbi.nlm.nih.gov/pubmed/30776286 http://dx.doi.org/10.1530/EC-18-0516 |