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Manganese Detoxification by MntE Is Critical for Resistance to Oxidative Stress and Virulence of Staphylococcus aureus

Manganese (Mn) is an essential micronutrient critical for the pathogenesis of Staphylococcus aureus, a significant cause of human morbidity and mortality. Paradoxically, excess Mn is toxic; therefore, maintenance of intracellular Mn homeostasis is required for survival. Here we describe a Mn exporte...

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Detalles Bibliográficos
Autores principales: Grunenwald, Caroline M., Choby, Jacob E., Juttukonda, Lillian J., Beavers, William N., Weiss, Andy, Torres, Victor J., Skaar, Eric P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391924/
https://www.ncbi.nlm.nih.gov/pubmed/30808698
http://dx.doi.org/10.1128/mBio.02915-18