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Metabolic Engineering of Bacillus subtilis Toward Taxadiene Biosynthesis as the First Committed Step for Taxol Production

Terpenoids are natural products known for their medicinal and commercial applications. Metabolic engineering of microbial hosts for the production of valuable compounds, such as artemisinin and Taxol, has gained vast interest in the last few decades. The Generally Regarded As Safe (GRAS) Bacillus su...

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Detalles Bibliográficos
Autores principales: Abdallah, Ingy I., Pramastya, Hegar, van Merkerk, Ronald, Sukrasno, Quax, Wim J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391936/
https://www.ncbi.nlm.nih.gov/pubmed/30842758
http://dx.doi.org/10.3389/fmicb.2019.00218