Cucurbit[8]uril Reactivation of an Inactivated Caspase‐8 Mutant Reveals Differentiated Enzymatic Substrate Processing

Caspase‐8 constructs featuring an N‐terminal FGG sequence allow for selective twofold recognition by cucurbit[8]uril, which leads to an increase of the enzymatic activity in a cucurbit[8]uril dose‐dependent manner. This supramolecular switching has enabled for the first time the study of the same ca...

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Detalles Bibliográficos
Autores principales: Dang, Dung T., van Onzen, Arthur H. A. M., Dorland, Yvonne L., Brunsveld, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391946/
https://www.ncbi.nlm.nih.gov/pubmed/30300966
http://dx.doi.org/10.1002/cbic.201800521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391946/
https://www.ncbi.nlm.nih.gov/pubmed/30300966
http://dx.doi.org/10.1002/cbic.201800521

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