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Palladium‐Catalyzed C(sp(3))−H Arylation of Primary Amines Using a Catalytic Alkyl Acetal to Form a Transient Directing Group

C−H Functionalization of amines is a prominent challenge due to the strong complexation of amines to transition metal catalysts, and therefore typically requires derivatization at nitrogen with a directing group. Transient directing groups (TDGs) permit C−H functionalization in a single operation, w...

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Detalles Bibliográficos
Autores principales: St John‐Campbell, Sahra, Ou, Alex K., Bull, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391947/
https://www.ncbi.nlm.nih.gov/pubmed/30255961
http://dx.doi.org/10.1002/chem.201804515

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