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Radical‐Mediated Thiol‐Ene Strategy: Photoactivation of Thiol‐Containing Drugs in Cancer Cells
Photoactivated drugs provide an opportunity to improve efficacy alongside reducing side‐effects in the treatment of severe diseases such as cancer. Described herein is a photoactivation decaging method of isobutylene‐caged thiols through a UV‐initiated thiol‐ene reaction. The method was demonstrated...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391964/ https://www.ncbi.nlm.nih.gov/pubmed/30300959 http://dx.doi.org/10.1002/anie.201811338 |