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Human‐Induced Pluripotent Stem Cells Generate Light Responsive Retinal Organoids with Variable and Nutrient‐Dependent Efficiency

The availability of in vitro models of the human retina in which to perform pharmacological and toxicological studies is an urgent and unmet need. An essential step for developing in vitro models of human retina is the ability to generate laminated, physiologically functional, and light‐responsive r...

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Detalles Bibliográficos
Autores principales: Hallam, Dean, Hilgen, Gerrit, Dorgau, Birthe, Zhu, Lili, Yu, Min, Bojic, Sanja, Hewitt, Philip, Schmitt, Michael, Uteng, Marianne, Kustermann, Stefan, Steel, David, Nicholds, Mike, Thomas, Robert, Treumann, Achim, Porter, Andrew, Sernagor, Evelyne, Armstrong, Lyle, Lako, Majlinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392112/
https://www.ncbi.nlm.nih.gov/pubmed/30004612
http://dx.doi.org/10.1002/stem.2883