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Isolating pulmonary microvascular endothelial cells ex vivo: Implications for pulmonary arterial hypertension, and a caution on the use of commercial biomaterials

Transcriptomic analysis of pulmonary microvascular endothelial cells from experimental models offers insight into pulmonary arterial hypertension (PAH) pathobiology. However, culturing may alter the molecular profile of endothelial cells prior to analysis, limiting the translational relevance of res...

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Detalles Bibliográficos
Autores principales: Wertheim, Bradley M., Lin, Yi-Dong, Zhang, Ying-Yi, Samokhin, Andriy O., Alba, George A., Arons, Elena, Yu, Paul B., Maron, Bradley A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392245/
https://www.ncbi.nlm.nih.gov/pubmed/30811450
http://dx.doi.org/10.1371/journal.pone.0211909