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Isolating pulmonary microvascular endothelial cells ex vivo: Implications for pulmonary arterial hypertension, and a caution on the use of commercial biomaterials
Transcriptomic analysis of pulmonary microvascular endothelial cells from experimental models offers insight into pulmonary arterial hypertension (PAH) pathobiology. However, culturing may alter the molecular profile of endothelial cells prior to analysis, limiting the translational relevance of res...
Autores principales: | Wertheim, Bradley M., Lin, Yi-Dong, Zhang, Ying-Yi, Samokhin, Andriy O., Alba, George A., Arons, Elena, Yu, Paul B., Maron, Bradley A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392245/ https://www.ncbi.nlm.nih.gov/pubmed/30811450 http://dx.doi.org/10.1371/journal.pone.0211909 |
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