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Drug sensitivity prediction with high-dimensional mixture regression

This paper proposes a mixture regression model-based method for drug sensitivity prediction. The proposed method explicitly addresses two fundamental issues in drug sensitivity prediction, namely, population heterogeneity and feature selection pertaining to each of the subpopulations. The mixture re...

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Detalles Bibliográficos
Autores principales: Li, Qianyun, Shi, Runmin, Liang, Faming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392252/
https://www.ncbi.nlm.nih.gov/pubmed/30811440
http://dx.doi.org/10.1371/journal.pone.0212108