Modulation of calcium signaling pathway by hepatitis C virus core protein stimulates NLRP3 inflammasome activation

Hepatitis C virus (HCV) infection remains a major cause of hepatic inflammation and liver disease. HCV triggers NLRP3 inflammasome activation and interleukin-1β (IL-1β) production from hepatic macrophages, or Kupffer cells, to drive the hepatic inflammatory response. Here we examined HCV activation...

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Detalles Bibliográficos
Autores principales: Negash, Amina A., Olson, Rebecca M., Griffin, Stephen, Gale, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392285/
https://www.ncbi.nlm.nih.gov/pubmed/30811485
http://dx.doi.org/10.1371/journal.ppat.1007593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392285/
https://www.ncbi.nlm.nih.gov/pubmed/30811485
http://dx.doi.org/10.1371/journal.ppat.1007593

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