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Modulation of calcium signaling pathway by hepatitis C virus core protein stimulates NLRP3 inflammasome activation
Hepatitis C virus (HCV) infection remains a major cause of hepatic inflammation and liver disease. HCV triggers NLRP3 inflammasome activation and interleukin-1β (IL-1β) production from hepatic macrophages, or Kupffer cells, to drive the hepatic inflammatory response. Here we examined HCV activation...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392285/ https://www.ncbi.nlm.nih.gov/pubmed/30811485 http://dx.doi.org/10.1371/journal.ppat.1007593 |