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The Wilms’ tumor suppressor gene regulates pancreas homeostasis and repair

The Wilms’ tumor suppressor gene (Wt1) encodes a zinc finger transcription factor that plays an essential role in the development of kidneys, gonads, spleen, adrenals and heart. Recent findings suggest that WT1 could also be playing physiological roles in adults. Systemic deletion of WT1 in mice pro...

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Detalles Bibliográficos
Autores principales: Ariza, Laura, Rojas, Anabel, Muñoz-Chápuli, Ramón, Carmona, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392337/
https://www.ncbi.nlm.nih.gov/pubmed/30763305
http://dx.doi.org/10.1371/journal.pgen.1007971