Coprevalence of parasitic infections and diabetes in Sub-Himalayan region of Northern India

OBJECTIVES: Parasitic infections such as toxoplasmosis, hydatidosis, and cysticercosis infect a large population worldwide. Toxoplasma gondii in the pancreas could damage the pancreatic cells. Hence, insulin secretion would be affected which leads to increased risk of diabetes. The present study was...

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Autores principales: Moudgil, Vaishali, Rana, Reetima, Tripathi, Praveen Kumar, Farooq, Umar, Sehgal, Rakesh, Khan, Mohammed Azhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Qassim Uninversity 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392483/
https://www.ncbi.nlm.nih.gov/pubmed/30842714
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author Moudgil, Vaishali
Rana, Reetima
Tripathi, Praveen Kumar
Farooq, Umar
Sehgal, Rakesh
Khan, Mohammed Azhar
author_facet Moudgil, Vaishali
Rana, Reetima
Tripathi, Praveen Kumar
Farooq, Umar
Sehgal, Rakesh
Khan, Mohammed Azhar
author_sort Moudgil, Vaishali
collection PubMed
description OBJECTIVES: Parasitic infections such as toxoplasmosis, hydatidosis, and cysticercosis infect a large population worldwide. Toxoplasma gondii in the pancreas could damage the pancreatic cells. Hence, insulin secretion would be affected which leads to increased risk of diabetes. The present study was designed to investigate the cooccurrence of parasitic infections in patients with diabetes. METHODS: A total of 256 confirmed parasitic serum samples were included in the study, of which 95 were positive for toxoplasmosis, 87 for hydatidosis, and 74 for cysticercosis infection. These samples were then analyzed for hyperglycemia. RESULTS: In case of hydatidosis, the frequency of hyperglycemia was 14.94%, followed by cysticercosis (10.8%) and toxoplasmosis (8.42%). The frequency of insulin resistance was analyzed in these hyperglycemic samples. The coprevalence of diabetes was higher in case of hyperglycemic hydatidosis patient samples (11.49%), followed by cysticercosis (8.10%) while the coprevalence of diabetes was minimum (6.31%) in toxoplasmosis patients samples. Thus, the overall prevalence of diabetes with parasitic infections was 8.6%. CONCLUSION: The study suggested the coexistence of hyperglycemia in hydatidosis, cysticercosis, and toxoplasmosis infected samples. However, higher prevalence of high glucose level was detected among hydatidosis infected samples. Thus, suggested individuals infected with hydatidosis were more susceptible for diabetes in comparison to toxoplasmosis and cysticercosis.
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spelling pubmed-63924832019-03-06 Coprevalence of parasitic infections and diabetes in Sub-Himalayan region of Northern India Moudgil, Vaishali Rana, Reetima Tripathi, Praveen Kumar Farooq, Umar Sehgal, Rakesh Khan, Mohammed Azhar Int J Health Sci (Qassim) Original Article OBJECTIVES: Parasitic infections such as toxoplasmosis, hydatidosis, and cysticercosis infect a large population worldwide. Toxoplasma gondii in the pancreas could damage the pancreatic cells. Hence, insulin secretion would be affected which leads to increased risk of diabetes. The present study was designed to investigate the cooccurrence of parasitic infections in patients with diabetes. METHODS: A total of 256 confirmed parasitic serum samples were included in the study, of which 95 were positive for toxoplasmosis, 87 for hydatidosis, and 74 for cysticercosis infection. These samples were then analyzed for hyperglycemia. RESULTS: In case of hydatidosis, the frequency of hyperglycemia was 14.94%, followed by cysticercosis (10.8%) and toxoplasmosis (8.42%). The frequency of insulin resistance was analyzed in these hyperglycemic samples. The coprevalence of diabetes was higher in case of hyperglycemic hydatidosis patient samples (11.49%), followed by cysticercosis (8.10%) while the coprevalence of diabetes was minimum (6.31%) in toxoplasmosis patients samples. Thus, the overall prevalence of diabetes with parasitic infections was 8.6%. CONCLUSION: The study suggested the coexistence of hyperglycemia in hydatidosis, cysticercosis, and toxoplasmosis infected samples. However, higher prevalence of high glucose level was detected among hydatidosis infected samples. Thus, suggested individuals infected with hydatidosis were more susceptible for diabetes in comparison to toxoplasmosis and cysticercosis. Qassim Uninversity 2019 /pmc/articles/PMC6392483/ /pubmed/30842714 Text en Copyright: © International Journal of Health Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Moudgil, Vaishali
Rana, Reetima
Tripathi, Praveen Kumar
Farooq, Umar
Sehgal, Rakesh
Khan, Mohammed Azhar
Coprevalence of parasitic infections and diabetes in Sub-Himalayan region of Northern India
title Coprevalence of parasitic infections and diabetes in Sub-Himalayan region of Northern India
title_full Coprevalence of parasitic infections and diabetes in Sub-Himalayan region of Northern India
title_fullStr Coprevalence of parasitic infections and diabetes in Sub-Himalayan region of Northern India
title_full_unstemmed Coprevalence of parasitic infections and diabetes in Sub-Himalayan region of Northern India
title_short Coprevalence of parasitic infections and diabetes in Sub-Himalayan region of Northern India
title_sort coprevalence of parasitic infections and diabetes in sub-himalayan region of northern india
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392483/
https://www.ncbi.nlm.nih.gov/pubmed/30842714
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