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Simultaneous involvement of 11q23 translocation resulting in chimeric MLL-AFF1 and a second translocation [t (9;21) (p13; p11.2)] in an infant acute lymphoblastic leukemia patient at relapse: A case report

RATIONALE: Three-way translocations occasionally occur in MLL-AFF1 fusion and other fusion gene. However, the complex chromosomal rearrangements in the study were the first report. PATIENT CONCERNS: We present novel cryptic and complex chromosomal rearrangements [der (21) t (9; 21) (p13; p11.2)] in...

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Detalles Bibliográficos
Autores principales: Liu, Guangming, Lu, Xianglan, Kim, Young Mi, Wang, Xianfu, Li, Shibo, Liu, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392770/
https://www.ncbi.nlm.nih.gov/pubmed/29794792
http://dx.doi.org/10.1097/MD.0000000000010874