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Maternal immunity and antibodies to dengue virus promote infection and Zika virus–induced microcephaly in fetuses

Zika virus (ZIKV), an emergent flaviviral pathogen, has been linked to microcephaly in neonates. Although the risk is greatest during the first trimester of pregnancy in humans, timing alone cannot explain why maternal ZIKV infection leads to severe microcephaly in some fetuses, but not others. The...

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Detalles Bibliográficos
Autores principales: Rathore, Abhay P. S., Saron, Wilfried A. A., Lim, Ting, Jahan, Nusrat, St. John, Ashley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392794/
https://www.ncbi.nlm.nih.gov/pubmed/30820456
http://dx.doi.org/10.1126/sciadv.aav3208