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MicroRNA-126 regulates the phosphatidylinositol-3 kinase (PI3K)/protein kinase B (AKT) pathway in SLK cells in vitro and the expression of its pathway members in Kaposi's sarcoma tissue

In vitro, microRNA-126 (miR-126) inhibits SLK cell proliferation, inhibits the cell cycle, induces cell apoptosis, and reduces cell invasiveness. Double luciferase assays have shown that phosphatidylinositol-3 kinase (PI3K) is the miR-126 target in SLK cells. We aimed to investigate the influence of...

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Detalles Bibliográficos
Autores principales: Lu, Gaihui, Wu, Xiujuan, Zhao, Zongfeng, Ding, Yuan, Wang, Peng, Wu, Caoying, Kang, Xiaojing, Pu, Xiongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392886/
https://www.ncbi.nlm.nih.gov/pubmed/30170375
http://dx.doi.org/10.1097/MD.0000000000011855