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Sodium rutin ameliorates Alzheimer’s disease–like pathology by enhancing microglial amyloid-β clearance

The accumulation of aggregated amyloid-β (Aβ) in the brain is the first critical step in the pathogenesis of Alzheimer’s disease (AD), which also includes synaptic impairment, neuroinflammation, neuronal loss, and eventual cognitive defects. Emerging evidence suggests that impairment of Aβ phagocyto...

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Detalles Bibliográficos
Autores principales: Pan, Rui-Yuan, Ma, Jun, Kong, Xiang-Xi, Wang, Xiao-Feng, Li, Shuo-Shuo, Qi, Xiao-Long, Yan, Yu-Han, Cheng, Jinbo, Liu, Qingsong, Jin, Wanzhu, Tan, Chang-Heng, Yuan, Zengqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393001/
https://www.ncbi.nlm.nih.gov/pubmed/30820451
http://dx.doi.org/10.1126/sciadv.aau6328