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Tenofovir alafenamide nephrotoxicity in an HIV-positive patient: A case report

RATIONALE: Tenofovir alafenamide (TAF) is novel prodrug of Tenofovir, a nucleotide reverse transcriptase inhibitor. TAF is less nephrotoxic than its predecessor prodrug, tenofovir disoproxil fumarate (TDF). Tenofovir causes mitochondrial dysfunction and tubular injury when there is elevated accumula...

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Detalles Bibliográficos
Autores principales: Novick, Tessa K., Choi, Michael J., Rosenberg, Avi Z., McMahon, Blaithin A., Fine, Derek, Atta, Mohamed G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393094/
https://www.ncbi.nlm.nih.gov/pubmed/28885375
http://dx.doi.org/10.1097/MD.0000000000008046