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Associations between ERAP1 polymorphisms and susceptibility to ankylosing spondylitis: A meta-analysis of East Asian Population

BACKGROUND: The genetic factor is importantly enrolled in the pathogenesis of ankylosing spondylitis (AS) and haplotype leukocyte antigen (HLA)-B27 is the most well-known. However, only 1% to 5% of B27-positive individuals will develop AS, and it confers only 20% to 30% of the overall genetic risks,...

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Detalles Bibliográficos
Autores principales: Jiang, Yuqing, Ren, Yi, Zhou, Dong, Xu, Youjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393156/
https://www.ncbi.nlm.nih.gov/pubmed/30461632
http://dx.doi.org/10.1097/MD.0000000000013263