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FOXO1 degradation via G9a-mediated methylation promotes cell proliferation in colon cancer

Posttranslational modifications of the Forkhead family transcription factor, FOXO1, have been known to have important regulatory implications in its diverse activities. Several types of modifications of FOXO1, including acetylation, phosphorylation, and ubiquitination, have been reported. However, l...

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Detalles Bibliográficos
Autores principales: Chae, Yun-Cheol, Kim, Ji-Young, Park, Jin Woo, Kim, Kee-Beom, Oh, Hyein, Lee, Kyung-Hwa, Seo, Sang-Beom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393239/
https://www.ncbi.nlm.nih.gov/pubmed/30535125
http://dx.doi.org/10.1093/nar/gky1230