Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing

Genetic manipulation via transgene overexpression, RNAi, or Cas9-based methods is central to biomedical research. Unfortunately, use of these tools is often limited by vector options. We have created a modular platform (pMVP) that allows a gene of interest to be studied in the context of an array of...

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Detalles Bibliográficos
Autores principales: Haldeman, Jonathan M, Conway, Amanda E, Arlotto, Michelle E, Slentz, Dorothy H, Muoio, Deborah M, Becker, Thomas C, Newgard, Christopher B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393299/
https://www.ncbi.nlm.nih.gov/pubmed/30590691
http://dx.doi.org/10.1093/nar/gky1286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393299/
https://www.ncbi.nlm.nih.gov/pubmed/30590691
http://dx.doi.org/10.1093/nar/gky1286

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