PCNA accelerates the nucleotide incorporation rate by DNA polymerase δ

DNA polymerase delta (Pol δ) is responsible for the elongation and maturation of Okazaki fragments in eukaryotic cells. Proliferating cell nuclear antigen (PCNA) recruits Pol δ to the DNA and serves as a processivity factor. Here, we show that PCNA also stimulates the catalytic rate of Saccharomyces...

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Detalles Bibliográficos
Autores principales: Mondol, Tanumoy, Stodola, Joseph L, Galletto, Roberto, Burgers, Peter M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393303/
https://www.ncbi.nlm.nih.gov/pubmed/30605530
http://dx.doi.org/10.1093/nar/gky1321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393303/
https://www.ncbi.nlm.nih.gov/pubmed/30605530
http://dx.doi.org/10.1093/nar/gky1321

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