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PCNA accelerates the nucleotide incorporation rate by DNA polymerase δ
DNA polymerase delta (Pol δ) is responsible for the elongation and maturation of Okazaki fragments in eukaryotic cells. Proliferating cell nuclear antigen (PCNA) recruits Pol δ to the DNA and serves as a processivity factor. Here, we show that PCNA also stimulates the catalytic rate of Saccharomyces...
Autores principales: | Mondol, Tanumoy, Stodola, Joseph L, Galletto, Roberto, Burgers, Peter M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393303/ https://www.ncbi.nlm.nih.gov/pubmed/30605530 http://dx.doi.org/10.1093/nar/gky1321 |
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