Complex DNA structures trigger copy number variation across the Plasmodium falciparum genome

Antimalarial resistance is a major obstacle in the eradication of the human malaria parasite, Plasmodium falciparum. Genome amplifications, a type of DNA copy number variation (CNV), facilitate overexpression of drug targets and contribute to parasite survival. Long monomeric A/T tracks are found at...

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Detalles Bibliográficos
Autores principales: Huckaby, Adam C, Granum, Claire S, Carey, Maureen A, Szlachta, Karol, Al-Barghouthi, Basel, Wang, Yuh-Hwa, Guler, Jennifer L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393310/
https://www.ncbi.nlm.nih.gov/pubmed/30576466
http://dx.doi.org/10.1093/nar/gky1268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393310/
https://www.ncbi.nlm.nih.gov/pubmed/30576466
http://dx.doi.org/10.1093/nar/gky1268

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