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Complex DNA structures trigger copy number variation across the Plasmodium falciparum genome
Antimalarial resistance is a major obstacle in the eradication of the human malaria parasite, Plasmodium falciparum. Genome amplifications, a type of DNA copy number variation (CNV), facilitate overexpression of drug targets and contribute to parasite survival. Long monomeric A/T tracks are found at...
Autores principales: | Huckaby, Adam C, Granum, Claire S, Carey, Maureen A, Szlachta, Karol, Al-Barghouthi, Basel, Wang, Yuh-Hwa, Guler, Jennifer L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393310/ https://www.ncbi.nlm.nih.gov/pubmed/30576466 http://dx.doi.org/10.1093/nar/gky1268 |
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