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Random mutagenesis of a hyperthermophilic archaeon identified tRNA modifications associated with cellular hyperthermotolerance

Random mutagenesis for the hyperthermophilic archaeon Thermococcus kodakarensis was established by the insertion of an artificial transposon designed to allow easy identification of the transposon-inserted locus. The phenotypic screening was applied for the isolation of thermosensitive mutants of T....

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Detalles Bibliográficos
Autores principales: Orita, Izumi, Futatsuishi, Ryohei, Adachi, Kyoko, Ohira, Takayuki, Kaneko, Akira, Minowa, Keiichi, Suzuki, Miho, Tamura, Takeshi, Nakamura, Satoshi, Imanaka, Tadayuki, Suzuki, Tsutomu, Fukui, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393311/
https://www.ncbi.nlm.nih.gov/pubmed/30605516
http://dx.doi.org/10.1093/nar/gky1313