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A novel Staphylococcus aureus cis–trans type I toxin–antitoxin module with dual effects on bacteria and host cells

Bacterial type I toxin–antitoxin (TA) systems are widespread, and consist of a stable toxic peptide whose expression is monitored by a labile RNA antitoxin. We characterized Staphylococcus aureus SprA2/SprA2(AS) module, which shares nucleotide similarities with the SprA1/SprA1(AS) TA system. We demo...

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Detalles Bibliográficos
Autores principales: Germain-Amiot, Noëlla, Augagneur, Yoann, Camberlein, Emilie, Nicolas, Irène, Lecureur, Valérie, Rouillon, Astrid, Felden, Brice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393315/
https://www.ncbi.nlm.nih.gov/pubmed/30544243
http://dx.doi.org/10.1093/nar/gky1257