Gene x Gene Interactions Highlight the Role of Incretin Resistance for Insulin Secretion

Introduction: Genetic polymorphisms in TCF7L2 are the strongest common risk variants for type 2 diabetes mellitus (T2D). We and others have shown that genetic variation in TCF7L2 and WFS1 affect incretin-stimulated insulin secretion. A recent genome-wide association study discovered genetic variants...

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Detalles Bibliográficos
Autores principales: Jaghutriz, Benjamin Assad, Heni, Martin, Lutz, Stefan Zoltán, Fritsche, Louise, Machicao, Fausto, Staiger, Harald, Peter, Andreas, Häring, Hans-Ulrich, Fritsche, Andreas, Wagner, Róbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393347/
https://www.ncbi.nlm.nih.gov/pubmed/30846969
http://dx.doi.org/10.3389/fendo.2019.00072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393347/
https://www.ncbi.nlm.nih.gov/pubmed/30846969
http://dx.doi.org/10.3389/fendo.2019.00072

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