Cocrystal Formation of Betulinic Acid and Ascorbic Acid: Synthesis, Physico-Chemical Assessment, Antioxidant, and Antiproliferative Activity

Betulinic acid (BA) was demonstrated to be a very promising anticancer agent against various tumor cell lines such as breast, colon, lung, and brain. Despite its strong cytotoxic effect, betulinic acid exhibits low water solubility, feature that is reflected in its poor bioavailability. To overcome...

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Detalles Bibliográficos
Autores principales: Nicolov, Mirela, Ghiulai, Roxana M., Voicu, Mirela, Mioc, Marius, Duse, Adina Octavia, Roman, Roxana, Ambrus, Rita, Zupko, Istvan, Moaca, Elena Alina, Coricovac, Dorina E., Farcas, Claudia, Racoviceanu, Roxana Marcela, Danciu, Corina, Dehelean, Cristina-Adriana, Soica, Codruta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393380/
https://www.ncbi.nlm.nih.gov/pubmed/30847340
http://dx.doi.org/10.3389/fchem.2019.00092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393380/
https://www.ncbi.nlm.nih.gov/pubmed/30847340
http://dx.doi.org/10.3389/fchem.2019.00092

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