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Single Cell Based Phosphorylation Profiling Identifies Alterations in Toll-Like Receptor 7 and 9 Signaling in Patients With Primary Sjögren's Syndrome

Primary Sjögren's syndrome (pSS) is associated with polymorphisms and mRNA expression profiles that are indicative of an exaggerated innate and type I IFN immune response. Excessive activation potential of signaling pathways may play a role in this profile, but the intracellular signaling profi...

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Detalles Bibliográficos
Autores principales: Davies, Richard, Sarkar, Irene, Hammenfors, Daniel, Bergum, Brith, Vogelsang, Petra, Solberg, Silje M., Gavasso, Sonia, Brun, Johan G., Jonsson, Roland, Appel, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393381/
https://www.ncbi.nlm.nih.gov/pubmed/30846988
http://dx.doi.org/10.3389/fimmu.2019.00281