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Single Cell Based Phosphorylation Profiling Identifies Alterations in Toll-Like Receptor 7 and 9 Signaling in Patients With Primary Sjögren's Syndrome
Primary Sjögren's syndrome (pSS) is associated with polymorphisms and mRNA expression profiles that are indicative of an exaggerated innate and type I IFN immune response. Excessive activation potential of signaling pathways may play a role in this profile, but the intracellular signaling profi...
Autores principales: | Davies, Richard, Sarkar, Irene, Hammenfors, Daniel, Bergum, Brith, Vogelsang, Petra, Solberg, Silje M., Gavasso, Sonia, Brun, Johan G., Jonsson, Roland, Appel, Silke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393381/ https://www.ncbi.nlm.nih.gov/pubmed/30846988 http://dx.doi.org/10.3389/fimmu.2019.00281 |
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