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Altered Regulation of Striatal Neuronal N-Methyl-D-Aspartate Receptor Trafficking by Palmitoylation in Huntington Disease Mouse Model

N-methyl-D-aspartate receptors (NMDARs) play a critical role in synaptic signaling, and alterations in the synaptic/extrasynaptic NMDAR balance affect neuronal survival. Studies have shown enhanced extrasynaptic GluN2B-type NMDAR (2B-NMDAR) activity in striatal neurons in the YAC128 mouse model of H...

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Detalles Bibliográficos
Autores principales: Kang, Rujun, Wang, Liang, Sanders, Shaun S., Zuo, Kurt, Hayden, Michael R., Raymond, Lynn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393405/
https://www.ncbi.nlm.nih.gov/pubmed/30846936
http://dx.doi.org/10.3389/fnsyn.2019.00003