Cargando…

Altered Regulation of Striatal Neuronal N-Methyl-D-Aspartate Receptor Trafficking by Palmitoylation in Huntington Disease Mouse Model

N-methyl-D-aspartate receptors (NMDARs) play a critical role in synaptic signaling, and alterations in the synaptic/extrasynaptic NMDAR balance affect neuronal survival. Studies have shown enhanced extrasynaptic GluN2B-type NMDAR (2B-NMDAR) activity in striatal neurons in the YAC128 mouse model of H...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kang, Rujun, Wang, Liang, Sanders, Shaun S., Zuo, Kurt, Hayden, Michael R., Raymond, Lynn A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393405/ https://www.ncbi.nlm.nih.gov/pubmed/30846936 http://dx.doi.org/10.3389/fnsyn.2019.00003

Ejemplares similares

Real-time imaging of glutamate clearance reveals normal striatal uptake in Huntington disease mouse models
por: Parsons, Matthew P., et al.
Publicado: (2016)

Striatal Synaptic Dysfunction and Hippocampal Plasticity Deficits in the Hu97/18 Mouse Model of Huntington Disease
por: Kolodziejczyk, Karolina, et al.
Publicado: (2014)

Altering cortical input unmasks synaptic phenotypes in the YAC128 cortico-striatal co-culture model of Huntington disease
por: Schmidt, Mandi E., et al.
Publicado: (2018)

The mechanism of degeneration of striatal neuronal subtypes in Huntington disease
por: Rikani, Azadeh A., et al.
Publicado: (2014)

mTORC1 Signaling Is Palmitoylation-Dependent in Hippocampal Neurons and Non-neuronal Cells and Involves Dynamic Palmitoylation of LAMTOR1 and mTOR
por: Sanders, Shaun S., et al.
Publicado: (2019)

Early Changes in Striatal Activity and Motor Kinematics in a Huntington's Disease Mouse Model
por: Koch, Ellen T., et al.
Publicado: (2022)

Striatal parvalbuminergic neurons are lost in Huntington's disease: implications for dystonia
por: Reiner, Anton, et al.
Publicado: (2013)

Huntington’s Disease and Striatal Signaling
por: Roze, Emmanuel, et al.
Publicado: (2011)

Gene therapy conversion of striatal astrocytes into GABAergic neurons in mouse models of Huntington’s disease
por: Wu, Zheng, et al.
Publicado: (2020)

Altered Balance of Activity in the Striatal Direct and Indirect Pathways in Mouse Models of Huntington's Disease
por: André, Véronique M., et al.
Publicado: (2011)

Alterations in striatal synaptic transmission are consistent across genetic mouse models of Huntington's disease
por: Cummings, Damian M, et al.
Publicado: (2010)

Transcriptional vulnerabilities of striatal neurons in human and rodent models of Huntington’s disease
por: Matsushima, Ayano, et al.
Publicado: (2023)

Altered enhancer transcription underlies Huntington’s disease striatal transcriptional signature
por: Le Gras, Stéphanie, et al.
Publicado: (2017)

Wild-type huntingtin ameliorates striatal neuronal atrophy but does not prevent other abnormalities in the YAC128 mouse model of Huntington disease
por: Van Raamsdonk, Jeremy M, et al.
Publicado: (2006)

Characterization of Striatal Neuronal Loss and Atrophy in the R6/2 Mouse Model of Huntington’s Disease
por: Dodds, Lindsay, et al.
Publicado: (2014)

Differential Alteration in Expression of Striatal GABA(A)R Subunits in Mouse Models of Huntington’s Disease
por: Du, Zhuowei, et al.
Publicado: (2017)

Palmitoylation regulates the intracellular trafficking and stability of c-Met
por: Coleman, David T., et al.
Publicado: (2016)

Acid sphingomyelinase regulates the localization and trafficking of palmitoylated proteins
por: Xiong, Xiahui, et al.
Publicado: (2019)

Cortical and Striatal Circuits in Huntington’s Disease
por: Blumenstock, Sonja, et al.
Publicado: (2020)

Striatal network modeling in Huntington’s Disease
por: Ponzi, Adam, et al.
Publicado: (2020)

Altered exocytosis of inhibitory synaptic vesicles at single presynaptic terminals of cultured striatal neurons in a knock-in mouse model of Huntington’s disease
por: Xu, Chen, et al.
Publicado: (2023)

Deficits in coordinated neuronal activity and network topology are striatal hallmarks in Huntington’s disease
por: Fernández-García, S., et al.
Publicado: (2020)

Neural Palmitoyl-Proteomics Reveals Dynamic Synaptic Palmitoylation
por: Kang, Rujun, et al.
Publicado: (2008)

Increasing brain palmitoylation rescues behavior and neuropathology in Huntington disease mice
por: Virlogeux, Amandine, et al.
Publicado: (2021)

Activity-regulated trafficking of the palmitoyl-acyl transferase DHHC5
por: Brigidi, G. Stefano, et al.
Publicado: (2015)

Palmitoylation-mediated synaptic regulation of AMPA receptor trafficking and function
por: Sohn, Heesung, et al.
Publicado: (2019)

DAPK1 Promotes Extrasynaptic GluN2B Phosphorylation and Striatal Spine Instability in the YAC128 Mouse Model of Huntington Disease
por: Schmidt, Mandi E., et al.
Publicado: (2020)

Mislocalization of Nucleocytoplasmic Transport Proteins in Human Huntington’s Disease PSC-Derived Striatal Neurons
por: Lange, Jenny, et al.
Publicado: (2021)

Impairment and Restoration of Homeostatic Plasticity in Cultured Cortical Neurons From a Mouse Model of Huntington Disease
por: Smith-Dijak, Amy I., et al.
Publicado: (2019)

Full-length huntingtin is palmitoylated at multiple sites and post-translationally myristoylated following caspase-cleavage
por: Lemarié, Fanny L., et al.
Publicado: (2023)

Early Deficits in Glycolysis Are Specific to Striatal Neurons from a Rat Model of Huntington Disease
por: Gouarné, Caroline, et al.
Publicado: (2013)

Mechanisms for regulation of RAS palmitoylation and plasma membrane trafficking in hematopoietic malignancies
por: Yu, Fang, et al.
Publicado: (2023)

Differential Synaptic and Extrasynaptic Glutamate-Receptor Alterations in Striatal Medium-Sized Spiny Neurons of Aged YAC128 Huntington’s Disease Mice
por: Botelho, Eliã P., et al.
Publicado: (2014)

Failure to Thrive: Impaired BDNF Transport along the Cortical–Striatal Axis in Mouse Q140 Neurons of Huntington’s Disease
por: Maloney, Michael T., et al.
Publicado: (2023)

Proteostasis in striatal cells and selective neurodegeneration in Huntington’s disease
por: Margulis, Julia, et al.
Publicado: (2014)

Striatal Vulnerability in Huntington’s Disease: Neuroprotection Versus Neurotoxicity
por: Morigaki, Ryoma, et al.
Publicado: (2017)

Striatal Network Models of Huntington's Disease Dysfunction Phenotypes
por: Zheng, Pengsheng, et al.
Publicado: (2017)

Changes in striatal activity and functional connectivity in a mouse model of Huntington's disease
por: Cabanas, Magali, et al.
Publicado: (2017)

Striatal Pre-Enkephalin Overexpression Improves Huntington’s Disease Symptoms in the R6/2 Mouse Model of Huntington’s Disease
por: Bissonnette, Stéphanie, et al.
Publicado: (2013)

Correction: Differential Synaptic and Extrasynaptic Glutamate-Receptor Alterations in Striatal Medium-Sized Spiny Neurons of Aged YAC128 Huntington's Disease Mice
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_2ofcicroqo7oulvcb239ft292i