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Novel Chitohexaose Analog Protects Young and Aged mice from CLP Induced Polymicrobial Sepsis

In Gram-negative bacterial sepsis, production of excess pro-inflammatory cytokines results in hyperinflammation and tissue injury. Anti-inflammatory cytokines such as IL-10 inhibit inflammation and enhance tissue healing. Here, we report a novel approach to treat septicemia associated with intra-abd...

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Detalles Bibliográficos
Autores principales: Das, Pragnya, Panda, Santosh K., Agarwal, Beamon, Behera, Sumita, Ali, Syed M., Pulse, Mark E., Solomkin, Joseph S., Opal, Steven M., Bhandari, Vineet, Acharya, Suchismita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393422/
https://www.ncbi.nlm.nih.gov/pubmed/30814582
http://dx.doi.org/10.1038/s41598-019-38731-3