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Integrative modeling reveals key chromatin and sequence signatures predicting super-enhancers
Super-enhancers (SEs) are clusters of transcriptional enhancers which control the expression of cell identity and disease-associated genes. Current studies demonstrated the role of multiple factors in SE formation; however, a systematic analysis to assess the relative predictive importance of chroma...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393462/ https://www.ncbi.nlm.nih.gov/pubmed/30814546 http://dx.doi.org/10.1038/s41598-019-38979-9 |