New fluoroethyl phenylalanine analogues as potential LAT1-targeting PET tracers for glioblastoma

The use of O-(2-[(18)F]fluoroethyl)-l-tyrosine ([(18)F]FET) as a positron emission tomography (PET) tracer for brain tumor imaging might have some limitations because of the relatively low affinity for the L-type amino acid transporter 1 (LAT1). To assess the stereospecificity and evaluate the influ...

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Detalles Bibliográficos
Autores principales: Verhoeven, Jeroen, Hulpia, Fabian, Kersemans, Ken, Bolcaen, Julie, De Lombaerde, Stef, Goeman, Jan, Descamps, Benedicte, Hallaert, Giorgio, Van den Broecke, Caroline, Deblaere, Karel, Vanhove, Christian, Van der Eycken, Johan, Van Calenbergh, Serge, Goethals, Ingeborg, De Vos, Filip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393465/
https://www.ncbi.nlm.nih.gov/pubmed/30814660
http://dx.doi.org/10.1038/s41598-019-40013-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393465/
https://www.ncbi.nlm.nih.gov/pubmed/30814660
http://dx.doi.org/10.1038/s41598-019-40013-x

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