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TIGAR promotes neural stem cell differentiation through acetyl-CoA-mediated histone acetylation

Cellular metabolism plays a crucial role in controlling the proliferation, differentiation, and quiescence of neural stem cells (NSCs). The metabolic transition from aerobic glycolysis to oxidative phosphorylation has been regarded as a hallmark of neuronal differentiation. Understanding what trigge...

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Detalles Bibliográficos
Autores principales: Zhou, Wenjuan, Zhao, Tiantian, Du, Jingyi, Ji, Guangyu, Li, Xinyue, Ji, Shufang, Tian, Wenyu, Wang, Xu, Hao, Aijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393469/
https://www.ncbi.nlm.nih.gov/pubmed/30814486
http://dx.doi.org/10.1038/s41419-019-1434-3