Fibroblast origin shapes tissue homeostasis, epidermal differentiation, and drug uptake

Preclinical studies frequently lack predictive value for human conditions. Human cell-based disease models that reflect patient heterogeneity may reduce the high failure rates of preclinical research. Herein, we investigated the impact of primary cell age and body region on skin homeostasis, epiderm...

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Detalles Bibliográficos
Autores principales: Hausmann, Christian, Zoschke, Christian, Wolff, Christopher, Darvin, Maxim E., Sochorová, Michaela, Kováčik, Andrej, Wanjiku, Barbara, Schumacher, Fabian, Tigges, Julia, Kleuser, Burkhard, Lademann, Jürgen, Fritsche, Ellen, Vávrová, Kateřina, Ma, Nan, Schäfer-Korting, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393472/
https://www.ncbi.nlm.nih.gov/pubmed/30814627
http://dx.doi.org/10.1038/s41598-019-39770-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393472/
https://www.ncbi.nlm.nih.gov/pubmed/30814627
http://dx.doi.org/10.1038/s41598-019-39770-6

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