An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics

Aging promotes lung function decline and susceptibility to chronic lung diseases, which are the third leading cause of death worldwide. Here, we use single cell transcriptomics and mass spectrometry-based proteomics to quantify changes in cellular activity states across 30 cell types and chart the l...

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Detalles Bibliográficos
Autores principales: Angelidis, Ilias, Simon, Lukas M., Fernandez, Isis E., Strunz, Maximilian, Mayr, Christoph H., Greiffo, Flavia R., Tsitsiridis, George, Ansari, Meshal, Graf, Elisabeth, Strom, Tim-Matthias, Nagendran, Monica, Desai, Tushar, Eickelberg, Oliver, Mann, Matthias, Theis, Fabian J., Schiller, Herbert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393476/
https://www.ncbi.nlm.nih.gov/pubmed/30814501
http://dx.doi.org/10.1038/s41467-019-08831-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393476/
https://www.ncbi.nlm.nih.gov/pubmed/30814501
http://dx.doi.org/10.1038/s41467-019-08831-9

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