Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis

Although hundreds of cytosolic or transmembrane molecules form the primary cilium, few secreted molecules are known to contribute to ciliogenesis. Here, homologous secreted metalloproteases ADAMTS9 and ADAMTS20 are identified as ciliogenesis regulators that act intracellularly. Secreted and furin-pr...

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Detalles Bibliográficos
Autores principales: Nandadasa, Sumeda, Kraft, Caroline M., Wang, Lauren W., O’Donnell, Anna, Patel, Rushabh, Gee, Heon Yung, Grobe, Kay, Cox, Timothy C., Hildebrandt, Friedhelm, Apte, Suneel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393521/
https://www.ncbi.nlm.nih.gov/pubmed/30814516
http://dx.doi.org/10.1038/s41467-019-08520-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393521/
https://www.ncbi.nlm.nih.gov/pubmed/30814516
http://dx.doi.org/10.1038/s41467-019-08520-7

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