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Vangl2 interaction plays a role in the proteasomal degradation of Prickle2

The PET and LIM domain-containing protein, Prickle, plays a key role in planar cell polarity (PCP) in Drosophila. It has been reported that mutations in the PRICKLE2 gene, which encodes one of the human orthologues of Prickle, are associated with human diseases such as epilepsy and autism spectrum d...

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Detalles Bibliográficos
Autores principales: Nagaoka, Tadahiro, Furuse, Mikio, Ohtsuka, Toshihisa, Tsuchida, Kunihiro, Kishi, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393536/
https://www.ncbi.nlm.nih.gov/pubmed/30814664
http://dx.doi.org/10.1038/s41598-019-39642-z