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Sortilin promotes glioblastoma invasion and mesenchymal transition through GSK-3β/β-catenin/twist pathway

High aggressiveness is a hallmark of glioblastoma and predicts poor prognosis of patients with glioblastoma. The expression level of sortilin has been preliminarily reported to be elevated in high-grade glioma; however, the potential significance of sortilin in glioblastoma progression has not been...

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Detalles Bibliográficos
Autores principales: Yang, Wei, Wu, Peng-fei, Ma, Jian-xing, Liao, Mao-jun, Wang, Xu-hui, Xu, Lun-shan, Xu, Min-hui, Yi, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393543/
https://www.ncbi.nlm.nih.gov/pubmed/30814514
http://dx.doi.org/10.1038/s41419-019-1449-9